In a new study, Fralin Biomedical Research Institute at VTC scientists discovered that the alphaCT1 molecule may help repair the skin's collagen matrix by altering how scar-forming cells behave. The findings were published in the Federation of American Societies for Experimental Biology Journal.
Even though KRAS4B is the dominant form in cancer, the KRAS4A mutant is also oncogenic, and it is even more active. In the words of the authors, "KRAS4AG12V alone, in the absence of KRAS4B, can induce lung cancer and metastasis in 20 percent of individuals. Our results suggest that for therapies to be effective, the two KRAS isoforms should be targeted."
Researchers are using computer models to simulate COVID-19 infections on a cellular level which allows for virtual trials of drugs and vaccines, opening the possibility of pre-assessment for drug and vaccine efficacy against the virus.
Wake Forest researchers and clinicians are using patient-specific tumor 'organoid' models as a preclinical companion platform to better evaluate immunotherapy treatment for appendiceal cancer,
A potentially game-changing treatment for people with, or at risk of, blood clots has been found effective by an international team of researchers led by McMaster University.
Firsthand reports from nurses in correctional facilities detail the challenges they faced during the COVID-19 pandemic.
Adolescent girls and young women can and will use HIV prevention products with consistency, according to interim results of a study being conducted in Africa of two different methods: daily use of the antiretroviral (ARV) tablet Truvada® as oral pre-exposure prophylaxis (PrEP) and the monthly dapivirine vaginal ring, a new HIV prevention product currently under regulatory review in several countries. This was not been the case in previous trials of either approach.
The latest investigations into a promising new genetic test for glaucoma - the leading cause of blindness worldwide - has found it has the ability to identify 15 times more people at high risk of glaucoma than an existing genetic test. The study, just published in JAMA Ophthalmology, builds on a long-running international collaboration between Flinders University and the QIMR Berghofer Medical Research Institute and other research partners around the world to identify genetic risk factors for glaucoma.
Pioneering 'printed metal' procedure to create bespoke treatment for early knee osteoarthritis set to be trialled in the UK following MHRA approval.
Kamil Gareev, Associate Professor at ETU "LETI," justified the prospects of using magnetotactic bacteria to treat malignant tumors.