Every spring, the Daylight Saving Time shift robs people of an hour of sleep - and a new study shows that DNA plays a role in how much the time change affects individuals. People whose genetic profile makes them more likely to be "early birds" can adjust to the time change in a few days. But those who tend to be "night owls" could take more than a week to get back on track.
1. Currently used SARS-CoV-2 vaccines more than 95% effective in preventing confirmed infection ; 2. Having sickle cell disease quadruples risk for COVID-19-related hospitalization and doubles risk for COVID-19-related death.
Study finds medications prescribed for children dropped by more than a quarter during the first eight months of the pandemic compared to the previous year, with the steepest declines in infection-related medicines like antibiotics and cough-and-cold drugs.
A new risk equation based on six routinely available laboratory tests identifies 2- and 4-year risk of kidney failure with high levels of accuracy among patients with chronic kidney disease
In an article published in AJKD, researchers found that among 176 studies on acute kidney injury, the KDIGO definitions of kidney injury were inconsistently applied and 80% of studies did not define recovery of kidney function.
High school students who participated in summer programs about public health increased their interest in pursuing careers in science, technology, engineering and mathematics (STEM), according to a Rutgers study.
Researchers at Michigan Medicine have discovered another functional autoantibody in COVID-19 patients that contributes to the disease's development and the "firestorm" of blood clots and inflammation it induces. The autoantibody makes it much harder for the body to degrade neutrophil extracellular traps, the toxic webs of DNA and proteins produced by overactive immune cells at heightened levels in COVID patients.
Even though KRAS4B is the dominant form in cancer, the KRAS4A mutant is also oncogenic, and it is even more active. In the words of the authors, "KRAS4AG12V alone, in the absence of KRAS4B, can induce lung cancer and metastasis in 20 percent of individuals. Our results suggest that for therapies to be effective, the two KRAS isoforms should be targeted."
What The Study Did: Researchers examined racial/ethnic disparities in outpatient visit rates to 29 physician specialties in the United States.
An observational study in Barcelona, Spain found that implementation of same-day rapid screening, use of face masks, and improved ventilation was associated with very low rates of SARS-CoV-2 transmission at an indoor mass-gathering live concert without physical distancing. The brief research report is published in Annals of Internal Medicine.