NYU Abu Dhabi researchers unlock secrets behind liver regrowth and regenerative medicine
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NYU Abu Dhabi (NYUAD) researchers uncovered a code that sets the genome of the liver to account for the remarkable ability for this organ to regenerate. This finding offers new insight into how the specific genes that promote regeneration can be activated when part of the liver is removed. These findings have the potential to inform the development of a new form of regenerative medicine that could help non-regenerative organs regrow in mice and humans.
Newborn mice lacking YAP1 gene are born without bile ducts. Curiously, they don't die in utero and remain physically active, if small and yellow-tinted.
Exercise training can help support management of overweight and obesity in adults, and can contribute to health benefits beyond "scale victories". The supplement published today in Obesity Reviews, based on the work of an expert group convened under the auspices of the European Association for the Study of Obesity (EASO), provides scientific evidence on health and wellbeing benefits of exercise training for people living with overweight and obesity.
Researchers at the University of Arizona believe the liver may hold the key to new, preventative Type 2 diabetes treatments.
New research from the University of California, Irvine reveals how the circadian regulation of glucose production in the liver is lost during lung cancer progression, and how the resulting increase in glucose production may fuel cancer cell growth.
Black patients with cirrhosis - late-stage liver disease - are about 25% more likely to die compared to non-Hispanic white patients and four times less likely to receive a liver transplant, reports a new study. Estimates of racial disparity in cirrhosis have been limited by a lack of large-scale longitudinal data. The paper is one of the first to link all seven large liver centers in Chicago with the death registry and transplant registry to examine racial disparities in cirrhosis.
Researchers at Karolinska Institutet in Sweden have analyzed and described in detail the immune cells residing in the human bile duct. The findings may pave the way for new treatment strategies against disorders of the bile duct, which are often linked to immunological processes. The study is published in the journal Science Translational Medicine.
Drinking coffee that is caffeinated (ground or instant) or decaffeinated is associated with a reduced risk of developing chronic liver disease and related liver conditions, according to a study published in the open access journal BMC Public Health.
A signaling protein thought to be able to treat liver damage in paracetamol toxicity could actually worsen it. Instead, Singapore scientists discovered, blocking its effects could be the way forward.
A rare parasitic infection imported from Europe continues to take root in Alberta. The province is now the North American hotspot for human alveolar echinococcosis (AE), which takes the form of a growth in the liver, causing serious and potentially deadly health complications.