
Compounds derived from hops show promise as treatment for common liver disease
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Research by Oregon State University suggests a pair of compounds originating from hops can help thwart a dangerous buildup of fat in the liver known as hepatic steatosis.
The number of people dying from cardiovascular disease (CVD) in Asia is increasing rapidly, with over half of all CVD deaths globally in 2019 occurring in Asian countries, according to a state-of-the-art review paper published in the inaugural issue of JACC: Asia. The data demonstrates an urgent need to understand the burdens and epidemiological features of CVD in Asian countries to develop localized CVD prevention strategies to combat the epidemic.
High running capacity is associated with health and longevity. However, whether high genetic running capacity promotes more efficient metabolism with aging is not known. A new study reveals that adipose tissue may have a key role in healthy aging.
A plant-based diet appears to afford significant protection to rats bred to become hypertensive on a high-salt diet, scientists report. When the rats become pregnant, the whole grain diet also protects the mothers and their offspring from deadly preeclampsia.
We analyzed cerebral tissues of the anterior cingulate cortex and superior temporal gyrus of schizophrenia cases and controls by using micro-CT. Mean curvatures of the capillary vessels showed a significant correlation to the mean curvatures of neurites, while the mean capillary diameter was almost constant, independent of the cases. The curved capillaries with a constant diameter should occupy a nearly constant volume, while neurons suffering from neurite thinning should have reduced volumes in schizophrenia
Research carried out by academics at NUI Galway and clinicians at University Hospital Galway Diabetes Centre, involving more than 4,500 patients in the west of Ireland, suggests that, despite careful medical management, a relatively high proportion of people with diabetes in Ireland are developing chronic kidney disease over time and are at risk of kidney failure and other complications of poor kidney function.
Medical University of South Carolina researchers have discovered a gatekeeper protein that destines developing cells in an embryo to become liver cells. It exposes the genetic material of the cells and marks them as 'ready' for differentiation, i.e., transformation into liver cells, when developmental conditions are right. The findings, published in Cell Reports, could help scientists to better understand why liver cells do not develop correctly in children with inherited liver diseases.
Salk researchers have identified how tumors cause immune cells to lose their ability to fight cancer, by producing harmful fats the energy-hungry immune cells ingest, impairing their functionality. The understanding opens new avenues for novel immunotherapies for cancer.
Researchers identify molecular mechanism for the anti-inflammatory activity of diabetes drug metformin and, in mouse studies, say it prevents lung inflammation in animals infected with SARS-CoV-2, the virus that causes COVID-19.
Despite knowing about decompression sickness - or 'the bends' - for more than a century, researchers are still mystified about how this condition occurs. A new study published by the open access journal Frontiers is the first to explore the genetic changes that occur in humans with the bends. It reveals that genes involved in white blood cell activation and inflammation are upregulated in divers with this condition. The results may pave the way for tests that allow doctors to diagnose decompression sickness more easily.