The findings, described in a study published in PLOS Genetics, expand on the complex role of a region of the genome of Wolbachia called Octomom, which is known to regulate its growth inside the host. And bring to light a paradox. If Octomom is deleted, Wolbachia grows uncontrolled inside the host. If amplified, with extra copies, it also grows uncontrolled. Both absence and excess lead to the same observable characteristic.
An estimated 8.4 billion people could be at risk from malaria and dengue by the end of the century if emissions keep rising at current levels, according to a new study published in The Lancet Planetary Health.
Wild fruits from Southern Africa show good potential to supplement diets with the building blocks of protein. Researchers from the University of Johannesburg studied 14 species. Two of the fruits contain several essential amino acids. All exceed the RDA for lysine. People can only obtain lysine from their food or supplements. Healthy development in children requires lysine. Maintaining a robust immune function also needs it, especially against viruses.
An international team including Lancaster University researchers has created a strategy for understanding the evolution of the COVID-19 pandemic throughout the African continent. Their COVID-19 surveillance strategy will improve the ability of African countries to interpret the complex data available to them during the pandemic.
In a new study, Molly Crockett, an associate professor of psychology at Yale, examined whether people trust leaders who make utilitarian decisions during a pandemic. To find out, she and her co-first authors -- Yale's Clara Colombatto and the University of Kent's Jim Everett -- assembled a multidisciplinary team of 37 international researchers to study people's trust in leaders around the globe.
Malaria still kills millions. Researchers are excited by a new intervention: giving people a drug which kills mosquitoes that bite them. Incredibly, this is a reality, as the drug ivermectin, widely used for the control of parasite infections such as lymphatic filariasis and onchocerciasis, appears to do this. With some mosquitoes now resistant to the insecticides used in treated bed nets, this is a potentially important new control measure.
New method provides information on spatial heat distribution in a wound to accurately predict whether VLUs will heal. The clinical study is the first to investigate textural analysis on VLUs using thermal images that do not require physical contact with the wound.
Two U.S. Phase 1 clinical trials of a novel candidate malaria vaccine have found that the regimen conferred unprecedentedly high levels of durable protection when volunteers were later exposed to disease-causing malaria parasites. The vaccine combines live parasites with either of two widely used antimalarial drugs -- an approach termed chemoprophylaxis vaccination. A Phase 2 clinical trial of the vaccine is now underway in Mali, a malaria-endemic country.
A new study in the Journal of the American Heart Association shows that a breathing exercise known as Inspiratory Muscle Strength Training can reduce blood pressure in weeks, with benefits on par with daily exercise or medication.
Among low-income, uninsured, or publicly insured women ages 25-64 years who were not up to date on cervical cancer screening, 72% perceived financial barriers to screening. The most commonly reported barriers were screening appointment costs (71%) and follow-up/future treatment costs (44%).