New study finds more than 4,000 songbirds can taste sugar, contrary to conventional wisdom.
DNA is composed of nucleobases represented by the letters A, T, G and C. But in a bacteriophage, another base, represented by the letter Z, exists. Scientists from the Institut Pasteur and the CNRS, in collaboration with the CEA, have now elucidated the biosynthesis pathway of this base. This work has been published in the April 30th, 2021 issue of Science.
Japanese researchers discovered that lipidated Atg8, the most famous factor that mediates autophagy, has membrane perturbation activity and elucidated that this activity is responsible for efficient autophagosome formation.
An international research group led by Kobe University's Professor TAKUMI Toru has revealed a causal gene (Necdin, NDN) in autism model mice that have the chromosomal abnormality called copy number variation. The researchers hope to illuminate this gene's molecular mechanism in order to contribute towards the creation of new treatment strategies for developmental disorders.
A new study by researchers at the University of Maryland provides a potential tool for unraveling the mystery of how experiences can cause inheritable changes to an animal's biology. By mating nematode worms, they produced permanent epigenetic changes that lasted for more than 300 generations. The research was published in the journal Nature Communications.
Researchers from the University of Sussex have determined the structure of a tiny multi-protein biological machine, furthering our understanding of human cells and helping to enhance research into cancer, neurodegeneration and other illnesses.
For the first time, Princess Margaret researchers have mapped out where and how leukemia begins and develops in infants with Down syndrome in preclinical models, paving the way to potentially prevent this cancer in the future.
A global consortium of scientists investigated which genetic factors influence severity of COVID-19. They found 13 locations in the human genome that are strongly associated with infection or severe COVID-19. They also identified causal factors such as smoking and high BMI. This study, one of the largest GWASs ever performed, includes nearly 50,000 COVID-19 patients and two million uninfected controls.
Researchers at the National Human Genome Research Institute (NHGRI), part of the National Institutes of Health (NIH), have developed the Families Sharing Health Assessment and Risk Evaluation (SHARE) workbook, which helps people use their family history to assess their risk for heart disease, diabetes, breast cancer and colorectal cancer.
Researchers from Qatar, alongside researchers from 24 other countries, contributed to the COVID-19 Host Genetics Initiative large analysis identifying genetic markers for COVID risks, published today in Nature. The results of the analysis will enable genetic tests to predict the course of the disease, potential targeted therapies and drug repurposing to treat new infections and "long COVID". It is the latest milestone establishing Qatar as a leading regional center for genomics research and precision medicine.