As the ravages of the opioid epidemic lead many to avoid these powerful painkillers, a significant number of people with fibromyalgia are finding an effective replacement in CBD-containing products, finds a new Michigan Medicine study.
COVID-19 can be mild, or even without symptoms at all. But it can also cause severe disease, leading to respiratory problems, organ failure, and death. Research on the immune mechanisms involved in people with severe COVID-19 has shown that they have widespread inflammation. Early on in the pandemic, several immunomodulatory anti-inflammatory treatments commonly used in people with rheumatic and musculoskeletal diseases (RMDs) were proposed as possible options for people with severe COVID-19.
During the continued progression of the Corona pandemic, rapid, inexpensive, and reliable tests will become increasingly important to determine whether people have the associated antibodies - either through infection or vaccination. Researchers at the Technical University of Munich (TUM) have now developed such a rapid antibody test. It provides the result in only eight minutes; the aim is to further reduce the process time to four minutes.
Intra-articular therapies (IAT) are frequently used to treat joint conditions such as gout, rheumatoid arthritis, or osteoarthritis. The procedure involves inserting a needle into the space between the bones of the joint to deliver a medicine. The types of medicines used in IAT techniques vary, from steroids to radiopharmaceuticals.
Monoclonal antibodies work well in reducing COVID-19 related emergency department visits and hospitalizations when administered early to high-risk patients, a study by the University of South Florida Health (USF Health) and Tampa General Hospital demonstrates. If used under FDA guidelines, the researchers suggest, this treatment can ease the pandemic's continuing burden on patients and on limited health care resources.
A groundbreaking study found that stem cells reduce the amount of virus causing AIDS, boost the body's antiviral immunity, and restore the gut's lymphoid follicles damaged by HIV. It provided a roadmap for multi-pronged HIV eradication strategies.
A team of researchers at the NYU Tandon School of Engineering who previously reported on a responsive hydrogel, investigated its gelation at distinct temperatures and pH conditions. The study, "Self-assembly of stimuli-responsive coiled-coil fibrous hydrogels," appears in the Royal Society of Chemistry journal Soft Matter.
For patients who have inflammatory bowel syndrome (IBS), the condition is literally a pain in the gut. Chronic -- or long-term -- abdominal pain is common, and there are currently no effective treatment options for this debilitating symptom. In a new study in ACS Pharmacology & Translational Science, researchers identify a new potential source of relief: a molecule derived from spider venom. In experiments with mice, they found that one dose could stop symptoms associated with IBS pain.
Women who currently use hormonal contraceptives face more than a 2-fold higher risk of developing glaucoma, according to an analysis of electronic medical records for women aged 15-45 years from 2008 to 2018. The British Journal of Clinical Pharmacology analysis included 2,366 women who developed glaucoma and 9,464 controls.
Two mRNA vaccines against COVID-19 have proven safe and effective in clinical trials, as well as in the millions of people who have been vaccinated so far. But how prior SARS-CoV-2 infection affects vaccine response, and how long that response lasts, are still uncertain. Now, a new study in ACS Nano supports increasing evidence that people who had COVID-19 need only one vaccine dose, and that boosters could be necessary for everyone in the future.