News by Subject Medicine & Health

A prospective cohort study found that quitting smoking after being diagnosed with early-stage non-small cell lung cancer may slow disease progression and decrease mortality. Given that about half of all smokers continue to smoke after a lung cancer diagnosis, these findings present an opportunity to improve overall and progression-free survival in this type of cancer. The study is published in Annals of Internal Medicine.

Taken together these Oncotarget findings show that the CTD and OD domains of mtp53 R273H play critical roles in mutant p53 GOF that pertain to processes associated with DNA replication.

a new study shows that several hundred common chemicals, including pesticides, ingredients in consumer products, food additives, and drinking water contaminants, could increase the risk of breast cancer by causing cells in breast tissue to produce more of the hormones estrogen or progesterone.

The Oncotarget authors found that AIM2 inflammasome is at the crossroad between COPD and lung cancer in that its higher presence is correlated to lower survival rate of smoking COPD adenocarcinoma patients.

Together these Oncotarget results describe the first ever CAC case with a BRCAness genetic background.