How early is the course of COVID-19, mild or severe, determined? In Cell, researchers examined nasal cells sampled from patients at the time of diagnosis, looking for differences between those who developed severe disease and those who experienced a mild illness. Cells from patients who developed severe COVID-19 exhibited a more muted antiviral response. If the early stages of infection can determine disease severity, it opens a path for scientists to develop early therapeutic interventions.
A new radiotracer that detects iron in cancer cells has proven effective, opening the door for the advancement of iron-targeted therapies for cancer patients. The radiotracer, 18F-TRX, can be used to measure iron concentration in tumors, which can help predict whether a not the cancer will respond to treatment. This research was published in the July issue of The Journal of Nuclear Medicine.
A new study led by researchers from the University of Chicago shows that deep learning models trained on large sets of cancer genetic and tissue histology data can easily identify the institution that submitted the images.
According to ARRS' American Journal of Roentgenology (AJR), the standardized non-invasive clear cell likelihood score (ccLS)--derived from MRI--correlates with the growth rate of small renal masses (cT1a, <4 cm) and may help guide personalized management.
No one wants bad breath -- not when visiting friends and family, at a job interview, and especially not on a first date. Smelly breath can make things awkward, but it also is a natural warning sign, indicating that serious dental issues are occurring. Now, researchers reporting in ACS Nano have constructed a portable, thumb-sized device that diagnoses bad breath by quickly "sniffing" exhalations for the gas that makes it stinky -- hydrogen sulfide.
New research published in the Journal of Bone and Mineral Research has found that cognitive decline is linked with accelerated bone loss and an increased fracture risk in women.
Chronic lymphocytic leukemia (CLL) is the most common leukemia in the Western world. New research published in the Journal of Leukocyte Biology reveals that certain protein markers may indicate which patients have stable forms of CLL and which have more aggressive types.
A new risk equation based on six routinely available laboratory tests identifies 2- and 4-year risk of kidney failure with high levels of accuracy among patients with chronic kidney disease
In an article published in AJKD, researchers found that among 176 studies on acute kidney injury, the KDIGO definitions of kidney injury were inconsistently applied and 80% of studies did not define recovery of kidney function.
Researchers are using computer models to simulate COVID-19 infections on a cellular level which allows for virtual trials of drugs and vaccines, opening the possibility of pre-assessment for drug and vaccine efficacy against the virus.