A new study reports that among individuals who had an allergic reaction to their first mRNA COVID-19 vaccine dose, all who went on to receive a second dose tolerated it. Even some who experienced anaphylaxis following the first dose tolerated the second dose.
What The Study Did: Researchers examined the safety of the second dose of the Pfizer-BioNTech or Moderna COVID-19 vaccines in patients who experienced an allergic reaction to the first dose.
There are many reasons that an intranasal vaccine against the SARS-CoV-2 virus would be helpful in the fight against COVID-19 infections, University of Alabama at Birmingham immunologists Fran Lund, Ph.D., and Troy Randall, Ph.D., write in a viewpoint article in the journal Science.
Advanced technologies have been used to solve a long-standing mystery about why some people develop serious illness when they are infected with the malaria parasite, while others carry the infection asymptomatically.
Researchers at Cornell have developed a way to analyze how individual immune cells react to the bacteria that cause tuberculosis. It could pave the way for new vaccine strategies and provide insights into fighting other infectious diseases.
Older people appear to have fewer antibodies against the novel coronavirus, a new laboratory study from Oregon Health & Science University suggests. With vaccine uptake slowing in Oregon and across United States, researchers say their findings underscore the importance of promoting vaccinations in local communities.
The in-house development of a novel SARS-CoV-2 test, creation of the Molecular Diagnostics Lab at the Fralin Biomedical Research Institute, and their importance to public health are chronicled in a new article in Nature Communications.
Researchers at the University of Cincinnati College of Medicine have developed a computerized decision analytic model to compare projected outcomes of three vaccine strategies: a patient opts for a messenger RNA vaccine, a patient decides to get an adenovirus vector vaccine or the patient simply forgoes a vaccine altogether.
Top U.S. health agencies retain the trust of the vast majority of the American public, as does Dr. Anthony Fauci, according to a new survey from the Annenberg Public Policy Center. Public confidence has grown in the safety and effectiveness of vaccines to prevent Covid-19. But people who say they rely on conservative media have less confidence in Fauci and are more likely to accept misinformation and conspiracy theories.
An international team of researchers led by Kumamoto and Tokyo Universities (Japan) have shown that the L452R mutation of the SARS-CoV-2 spike protein, which is common to two variants (Epsilon and Delta), is involved in cellular immunity evasion via the human leukocyte antigen (HLA) A24, and enhances viral infectivity. HLA-A24 is one of the most prominent HLA-class I alleles, especially in East/Southeast Asian populations, which might make them particularly vulnerable to variants with the mutation.