Researchers have found that omega-3 levels in blood erythrocytes are very good mortality risk predictors. The study used data from a long-term study group, the Framingham Offspring Cohort, which has been monitoring residents of this Massachusetts town, in the United States, since 1971 and concludes that "Having higher levels of these acids in the blood, as a result of regularly including oily fish in the diet, increases life expectancy by almost five years",
Research Shows Employer-Based Weight Management Program With Access To Anti-Obesity Medications Results in Greater Weight Loss Clinical trial was conducted in the real-world setting of a workplace health plan A Cleveland Clinic study demonstrates that adults with obesity lost significantly more weight when they had access to medications for chronic weight management in conjunction with their employer-based weight management program, compared to adults who did not have access to the medications. The study was published in JAMA Network Open.
Researchers from Tokyo Medical and Dental University (TMDU) have identified important parts of the pathway by which a high-fat diet affects the body's immune response, leading eventually to atherosclerosis. Working with mouse models, they clarified how histone H3 citrullination activates neutrophils with serum CXCL1 elevation. Identifying these steps could lead to new diagnostic tools and treatments for cardiovascular disease.
In a new study published in Circulation research, Chen-Yu Zhang and Xiaohong Jiang's group from Nanjing University and Dongjin Wang's group from Nanjing Drum Tower Hospital reported a critical role of PGC1α in maintaining the contractile phenotype of vascular smooth muscle cells (VSMCs) and highlighted the therapeutic potential of PGC1α for atherosclerosis.
Previously measured risk factors could help to prevent potentially fatal cardiovascular diseases and help in targeting preventive interventions.
Statin use among patients with heart failure is associated with a 16% lower risk of developing cancer compared with non-statin users during an average of four years of follow-up, according to new research published in the European Heart Journal. In addition, the study found that statin use was associated with a 26% reduced risk of dying from cancer over the same period.
New research from the University of Bath's Centre for Nutrition, Exercise & Metabolism suggests that if you want to lose weight, intermittent fasting such as the 5:2 diet might be less effective than many people believe.
The alterations detected link obesity to a brain condition similar to obsessive-compulsive disorder, which affects the same areas of the brain. Researchers analysed images of the brains of 230 children obtained by functional magnetic resonance imaging. This was the first study of these features in children. They believe the findings underscore the need for early intervention in child obesity, in order to prevent the alterations from becoming fixed in children's developing brains.
Scientists studying the link between cholesterol and breast cancer report that a byproduct of cholesterol metabolism causes some cells to send out cancer-promoting signals to other cells. These signals are packaged in membrane-bound compartments called extracellular vesicles.
Millions of adults could lower the chance that they'll ever need a drug to treat dementia including Alzheimer's disease, if they work with their primary care providers and use the power of prevention to keep their brains healthy. A recent review by a national panel of experts summarizes the evidence behind steps providers and patients can take to identify and change modifiable risk factors.