New research published in the Journal of Bone and Mineral Research has found that cognitive decline is linked with accelerated bone loss and an increased fracture risk in women.
Electrical activity in the motor cortex of rats transforms from redundant to complex over the span of four days shortly after birth. Sleep twitches guide this metamorphosis, according to new research published in JNeurosci.
Physical relaxation through yoga or other practices can help reduce work-related stress, according to an analysis of studies conducted in healthcare staff.
Researchers from the University of Tsukuba have found that nuclear factor E2-related factor 2, a master regulator of the oxidative stress response, affects muscle composition in microgravity. Targeting this protein could help protect against muscle changes during space flight, and could also have implications for muscle wasting in conditions such as cancer and aging.
Muscles and the resident stem cells (satellite cells) responsible for muscle regeneration retain memory of their location in the body. This positional memory was found to be based on the expression pattern of the homeobox (Hox) gene cluster, which is responsible for shaping the body during fetal life. These findings are expected to provide clues to elucidate the pathogenesis of muscle diseases like muscular dystrophy, and help develop regenerative treatments based on positional memory.
Researchers at Harvard's Wyss Institute for Biologically Inspired Engineering and John A. Paulson School of Engineering and Applied Sciences (SEAS) have developed a new approach in which specifically designed anti-inflammatory nanoparticles (NPs) that could be applied locally and selectively to chronically inflamed muscles severely affected or at more immediate risk of deterioration, and maybe difficult to reach with oral therapeutics.
Mount Sinai Study Finds That Rotator Cuff Injuries Account for Nearly Half of Shoulder Injuries Among Collegiate Baseball Players, Identifies Other Risks
What The Study Did: The incidence of Bell palsy among patients with COVID-19 was compared with individuals vaccinated against the disease.
Diet rich in sugar and fat leads to disruption in the gut's microbial culture and contributes to inflammatory skin diseases such as psoriasis. Research shows that switching to a more balanced diet restores the gut's health and suppresses inflammation.
Researchers from University of Tsukuba, in collaboration with scientists in Germany, have created a mouse model of restrictive cardiomyopathy, a disease in which the heart muscle becomes stiff and the heart is unable to properly fill with blood. Their data suggest that the disease results from the accumulation of mutant BAG3 protein, which interferes with the protein quality control system and the machinery for breaking down and recycling damaged proteins, disrupting the heart muscle components.