Transcriptional Profiling of Obese and Nonobese (image)

Cell Press

Caption

This graphic abstract represents the findings of Ryden et al, who performed transcriptomic profiling in adipose tissue from nonobese and obese subjects discordant in insulin sensitivity. The transcriptional response to hyperinsulinemia was similar among obese subjects and differed from that in non-obese subjects. The two obese groups differed only in a limited set of genes, thereby challenging the notion of healthy obesity.

Credit

Ryden et al./Cell Reports 2016

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