Getting Cells to Move (image)

Cincinnati Children's Hospital Medical Center

Caption

These images from scientists at Cincinnati Children's show hematopoietic stem cells (blood stem cells) from donor laboratory mice. The donor stem cell harvested from a mouse treated with the preclinical drug CASIN (bottom) is depolarized with several colored polarity markers -- giving it better mobilization potential than the untreated stem cell in the top image. The scientists report in the journal Leukemia that preclinical data show CASIN treatment has the potential to make life-saving bone marrow transplant procedures safer and more effective for patients.

Credit

Cincinnati Children's

Usage Restrictions

Please credit Cincinnati Children's

Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.